Serum unconjugated bisphenol A concentrations in women may adversely influence oocyte quality during in vitro fertilization.
نویسندگان
چکیده
Bisphenol A (BPA) is an endocrine disruptor with estrogenic properties that can adversely affect meiotic spindle assemblies. Our data indicate that BPA exposure in female patients may interfere with oocyte quality during IVF, as suggested by the inverse association between serum unconjugated BPA concentration and normal fertilization.
منابع مشابه
Serum unconjugated bisphenol A concentrations in men may influence embryo quality indicators during in vitro fertilization.
Here we assess bisphenol A (BPA) in couples undergoing in vitro fertilization (IVF) and indicators of embryo quality; embryo cell number (ECN) and embryo fragmentation score (EFS). Twenty-seven couples provided serum on the day of oocyte retrieval. Unconjugated BPA was measured by HPLC with Coularray detection. Odds ratios (OR) were generated using ordinal logistic regression including female a...
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OBJECTIVE To investigate associations between serum bisphenol A (BPA) concentrations and follicular response to exogenous ovary stimulation. DESIGN Fasting serum was prospectively collected on the day of oocyte retrieval and assessed for unconjugated BPA using high-performance liquid chromatography with Coularray detection. Multivariable linear regression and negative binomial regression were...
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ورودعنوان ژورنال:
- Fertility and sterility
دوره 95 5 شماره
صفحات -
تاریخ انتشار 2011